treat chronic diseases

INFEPERIUM™

A breakthrough Immunotherapy and why it is different!

WARNING!!! This page is for licensed physicians and medical researchers. See disclaimer below.

Immunotherapy and Biological Response Modifiers

Immunotherapy and biological response modifiers (BRMs) are closely related, as both involve the use of the body’s immune system to fight diseases, including cancer, infections, and autoimmune conditions. However, there are distinctions between the two:

Immunotherapy:
Definition: Immunotherapy refers to a broad range of treatments that harness and enhance the body’s immune system to fight diseases, particularly cancer. It works by either stimulating the immune system to work harder or providing components (like antibodies) to bolster its response.

Types:

  • Checkpoint Inhibitors: Drugs that block proteins like PD-1/PD-L1 or CTLA-4, allowing T-cells to attack cancer cells.
  • CAR-T Cell Therapy: Genetically engineered T-cells that specifically target cancer cells.
  • Cancer Vaccines: Stimulate the immune system against cancer-specific antigens.
  • Cytokines: Proteins like interleukins and interferons to boost immune activity.
  • Monoclonal Antibodies: Lab-made molecules that target specific proteins on cancer cells or enhance immune response.

Biological Response Modifiers (BRMs)
Definition: BRMs are a subset of immunotherapy that specifically alter the interaction between the immune system and cancer cells to either boost the immune response or suppress mechanisms that inhibit it. BRMs can also be used to manage side effects of other treatments.

Types:

  • Cytokines: Natural or synthetic versions of proteins (e.g., interferons, interleukins) that regulate immune responses.
  • Growth Factors: Help repair and regenerate cells after treatments like chemotherapy.
  • Vaccines: Stimulate immune responses by introducing antigens to the body.
  • Monoclonal Antibodies: These can serve as BRMs when used to enhance immune activity.

Differences:
Scope:

  • Immunotherapy encompasses a broader range of treatments, including BRMs and other advanced therapies like CAR-T cells.
  • BRMs are specifically focused on modifying the biological environment to regulate immune responses.

Mechanism:

  • Immunotherapy may directly target cancer or pathogens (e.g., using CAR-T cells).
  • BRMs mainly focus on enhancing or modulating the immune system's interaction with the disease.

Use in Conditions:

  • Immunotherapy is predominantly associated with cancer and some infectious or autoimmune diseases.
  • BRMs are often used for cancer, autoimmune diseases, and managing treatment side effects.

Summary:
While BRMs are a form of immunotherapy, not all immunotherapies are BRMs. BRMs are specific agents that modify biological responses, whereas immunotherapy can include other broader strategies to engage the immune system.

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